In situ evaluation of podocytes in patients with focal segmental glomerulosclerosis and minimal change disease.
Podocyte injury in focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) results from the imbalance between adaptive responses that maintain homeostasis and cellular dysfunction that can culminate in cell death.Therefore, an in situ analysis was performed to detect morphological changes related to cell death and autophagy in re